Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 2.276


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMARCC2chr12_-_548695680.783.4e-04Click!
DMAP1chr1_+_444516980.611.3e-02Click!
SMARCA1chrX_-_128485121-0.514.2e-02Click!
SMARCA5chr4_+_144654005-0.371.6e-01Click!
NCOR1chr17_-_159144850.292.8e-01Click!
NCOR2chr12_-_1236179620.243.6e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_42815851 6.717 NM_080745
NM_182985
TRIM69

tripartite motif containing 69

chr3_+_120799411 6.193 NM_015900
PLA1A
phospholipase A1 member A
chrX_+_78087484 5.597 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr5_-_138753443 5.397 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr10_-_11614279 5.309 NM_001080491
USP6NL
USP6 N-terminal like
chr16_+_48865521 4.869 ADCY7
adenylate cyclase 7
chr3_+_123279439 4.829 NM_006889
CD86
CD86 molecule
chrX_-_30505804 4.763 NM_025159
CXorf21
chromosome X open reading frame 21
chr16_+_10878539 4.514 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chr7_+_73826244 4.490 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr13_+_23042722 4.482 NM_148957
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr2_+_143603439 3.966 ARHGAP15
Rho GTPase activating protein 15
chr14_+_99601498 3.869 NM_016337
EVL
Enah/Vasp-like
chr14_+_99601517 3.869 EVL
Enah/Vasp-like
chr2_+_143603368 3.820 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr19_+_17377502 3.772 LOC100507535
hypothetical LOC100507535
chr14_+_75058518 3.732 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr12_-_15005761 3.698 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr14_+_75058591 3.688 BATF
basic leucine zipper transcription factor, ATF-like
chr5_-_169657312 3.650 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr22_-_25205376 3.647 NM_152841
HPS4
Hermansky-Pudlak syndrome 4
chr1_+_165564904 3.641 NM_001198783
POU2F1
POU class 2 homeobox 1
chr1_+_165565006 3.587 POU2F1
POU class 2 homeobox 1
chr1_-_205161821 3.526 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr17_-_78000890 3.516 NM_001193655
C17orf62
chromosome 17 open reading frame 62
chr5_-_169657192 3.281 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr17_+_55854636 3.208 NM_181707
C17orf64
chromosome 17 open reading frame 64
chr6_-_33016561 3.200 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr5_-_169657395 3.046 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr17_+_44643067 3.040 ABI3
ABI family, member 3
chr19_-_10074332 3.012 NM_031917
ANGPTL6
angiopoietin-like 6
chr20_+_44180355 2.912 CD40
CD40 molecule, TNF receptor superfamily member 5
chr20_+_44180296 2.908 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr5_-_149772528 2.847


chr5_-_169657360 2.830 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_149772469 2.749 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr17_-_44642934 2.645 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr19_-_2036227 2.611 MOBKL2A
MOB1, Mps One Binder kinase activator-like 2A (yeast)
chr1_-_159306327 2.588 ARHGAP30
Rho GTPase activating protein 30
chr4_+_39874921 2.582 NM_004310
RHOH
ras homolog gene family, member H
chr19_+_17723285 2.579 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr17_+_6600080 2.576 XAF1
XIAP associated factor 1
chr6_+_70633168 2.503 NM_001858
COL19A1
collagen, type XIX, alpha 1
chr6_+_31647854 2.452 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr17_+_22823151 2.448 NM_014238
KSR1
kinase suppressor of ras 1
chr1_+_196874839 2.446 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_32489426 2.413 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr11_+_5602782 2.386 NM_021616
TRIM34
tripartite motif containing 34
chr19_-_44518465 2.374 GMFG
glia maturation factor, gamma
chr6_+_52159143 2.342 NM_002190
IL17A
interleukin 17A
chr7_+_73145481 2.333 LIMK1
LIM domain kinase 1
chr19_-_44518516 2.325 NM_004877
GMFG
glia maturation factor, gamma
chr15_+_86983038 2.324 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chrX_+_37524190 2.323 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr11_+_303852 2.311 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr12_+_25096472 2.200 NM_006152
LRMP
lymphoid-restricted membrane protein
chr1_-_159306369 2.147 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr18_+_13601664 2.092 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr5_-_142795269 2.030 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr12_-_119961143 2.023 NM_003733
NM_198213
OASL

2'-5'-oligoadenylate synthetase-like

chr19_-_40925151 2.010 NM_024660
TMEM149
transmembrane protein 149
chr7_+_128795178 1.983 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr12_-_9777126 1.976 NM_172004
CLECL1
C-type lectin-like 1
chrX_+_37524250 1.951 CYBB
cytochrome b-245, beta polypeptide
chr7_+_128795280 1.917 AHCYL2
adenosylhomocysteinase-like 2
chr6_+_29799182 1.914 HLA-F
major histocompatibility complex, class I, F
chr17_-_31231421 1.914 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr7_-_76667045 1.896 NM_006682
FGL2
fibrinogen-like 2
chr19_-_17377383 1.883 NM_004335
BST2
bone marrow stromal cell antigen 2
chr13_-_102517196 1.849 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr22_+_38627031 1.845 NM_004810
GRAP2
GRB2-related adaptor protein 2
chr3_-_49826221 1.828 UBA7
ubiquitin-like modifier activating enzyme 7
chr9_+_126460511 1.825


chr7_+_28418668 1.818 NM_182898
CREB5
cAMP responsive element binding protein 5
chr2_-_213723298 1.806 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr5_-_149772563 1.778 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr3_-_113495763 1.778 NM_183061
SLC9A10
solute carrier family 9, member 10
chr17_-_26665213 1.773 EVI2B
ecotropic viral integration site 2B
chr3_+_188568861 1.764 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr1_+_78888064 1.691 NM_006417
IFI44
interferon-induced protein 44
chr12_+_11694172 1.667 ETV6
ets variant 6
chr13_-_45654327 1.661 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_196874759 1.641 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr5_-_94442941 1.588 MCTP1
multiple C2 domains, transmembrane 1
chr16_+_11966464 1.558 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr17_-_31441390 1.531 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr16_+_55580910 1.512 NM_032206
NLRC5
NLR family, CARD domain containing 5
chr11_-_104421240 1.473 NM_001017534
NM_052889
CARD16

CASP1
caspase recruitment domain family, member 16

caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr6_-_149847718 1.464 ZC3H12D
zinc finger CCCH-type containing 12D
chr3_-_42789738 1.451 NM_144719
CCDC13
coiled-coil domain containing 13
chr11_-_104411065 1.433 NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CASP1




caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr4_+_113958652 1.431 NM_001127493
ANK2
ankyrin 2, neuronal
chr10_-_7491204 1.408 NM_001018039
SFMBT2
Scm-like with four mbt domains 2
chr11_+_71387572 1.406 NM_001039659
NM_001039660
NM_173042
IL18BP


interleukin 18 binding protein


chr22_+_38627129 1.395 GRAP2
GRB2-related adaptor protein 2
chr4_-_87500201 1.389 MAPK10
mitogen-activated protein kinase 10
chr22_-_37480898 1.382 SUN2
Sad1 and UNC84 domain containing 2
chr11_+_71388310 1.372 NM_001145057
IL18BP
interleukin 18 binding protein
chr1_-_153098811 1.362 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr4_-_153820535 1.343 NM_152680
TMEM154
transmembrane protein 154
chr17_+_7402788 1.320 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr7_+_119700924 1.315 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr12_-_47604930 1.310 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr17_+_6599879 1.301 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr1_-_149004916 1.292 NM_004079
CTSS
cathepsin S
chr18_+_71051713 1.282 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr10_-_1769669 1.277 NM_018702
ADARB2
adenosine deaminase, RNA-specific, B2
chr6_-_138231006 1.271


chr1_-_9052253 1.257 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr2_+_218641982 1.254 NM_198483
RUFY4
RUN and FYVE domain containing 4
chr17_-_37518213 1.253 NM_024119
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr1_-_9052170 1.233 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_-_149847809 1.219 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr3_+_190831909 1.212 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr11_+_128068982 1.211 NM_002017
FLI1
Friend leukemia virus integration 1
chr17_+_44642587 1.208 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr11_+_5667494 1.194 NM_006074
TRIM22
tripartite motif containing 22
chr12_+_6431437 1.191 NM_018009
TAPBPL
TAP binding protein-like
chr17_-_26665144 1.180 EVI2B
ecotropic viral integration site 2B
chr16_-_28425632 1.170 NM_145659
IL27
interleukin 27
chr4_-_38482805 1.161 NM_003263
TLR1
toll-like receptor 1
chr1_+_84539876 1.154 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr2_-_37752731 1.144 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr1_-_181889070 1.143 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr5_-_88155360 1.138 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr16_-_49272741 1.135 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr1_-_149004879 1.130 CTSS
cathepsin S
chr1_+_159943385 1.128 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr12_+_91620749 1.121 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chrX_-_131401319 1.119 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr1_+_157441824 1.116 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr3_-_114176401 1.094 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr1_-_149586298 1.093 RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr12_-_623056 1.083


chr19_+_40895669 1.074 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr19_+_10057972 1.065 C19orf66
chromosome 19 open reading frame 66
chr12_+_119562737 1.063 NM_001033677
CABP1
calcium binding protein 1
chr1_+_938709 1.048 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr20_-_51633042 1.046 NM_006526
ZNF217
zinc finger protein 217
chr13_+_23742846 1.031 SPATA13
spermatogenesis associated 13
chr10_+_114125955 1.024 ACSL5
acyl-CoA synthetase long-chain family member 5
chr16_-_88358946 1.021 FANCA
Fanconi anemia, complementation group A
chr12_-_51887318 1.020 ITGB7
integrin, beta 7
chr12_-_47605478 1.016 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chr14_+_23700261 1.004 NM_006084
IRF9
interferon regulatory factor 9
chr11_+_71388619 1.002 NM_001145055
IL18BP
interleukin 18 binding protein
chr19_-_55104875 0.995 NUP62
nucleoporin 62kDa
chr12_+_25096755 0.993 LRMP
lymphoid-restricted membrane protein
chr1_-_25164061 0.991 NM_001031680
RUNX3
runt-related transcription factor 3
chr5_-_137502975 0.991 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr11_+_63060848 0.986 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr4_+_38740246 0.983 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr1_-_149004852 0.970 CTSS
cathepsin S
chr7_+_150013716 0.954 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr10_+_35466715 0.954 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr10_+_91082218 0.944 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr1_+_67404756 0.934 NM_144701
IL23R
interleukin 23 receptor
chr7_+_106293112 0.929 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr17_-_26665194 0.927 EVI2B
ecotropic viral integration site 2B
chr12_-_51887266 0.919 NM_000889
ITGB7
integrin, beta 7
chr16_+_29726962 0.911 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr6_+_29799095 0.910 NM_001098478
NM_001098479
NM_018950
HLA-F


major histocompatibility complex, class I, F


chr1_+_100957883 0.908 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr16_+_29726931 0.896 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr8_-_102872372 0.881 NCALD
neurocalcin delta
chr3_-_58175437 0.878 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr14_-_22358752 0.877 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr9_+_127550298 0.853 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chr1_+_196874867 0.852 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_-_149586341 0.849 NM_000449
NM_001025603
RFX5

regulatory factor X, 5 (influences HLA class II expression)

chr8_-_102872354 0.846 NCALD
neurocalcin delta
chr15_-_42790805 0.844


chr1_-_159099090 0.844 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr2_+_182030510 0.840 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr9_-_5294579 0.837 NM_005059
NM_134441
RLN2

relaxin 2

chr17_-_39094787 0.831 NM_001040002
MEOX1
mesenchyme homeobox 1
chr8_-_145132582 0.812 NM_032789
PARP10
poly (ADP-ribose) polymerase family, member 10
chr17_-_26665220 0.805 NM_006495
EVI2B
ecotropic viral integration site 2B
chr3_-_49370682 0.804 GPX1
glutathione peroxidase 1
chr16_+_27346079 0.798 NM_021798
IL21R
interleukin 21 receptor
chr19_+_10058023 0.797 C19orf66
chromosome 19 open reading frame 66
chr5_-_94443300 0.782 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr8_-_145132551 0.781 PARP10
poly (ADP-ribose) polymerase family, member 10
chr19_+_40511909 0.774 NM_001185099
NM_001185100
NM_001185101
NM_001771
CD22



CD22 molecule



chr5_-_176671437 0.769 MXD3
MAX dimerization protein 3
chr3_+_99733432 0.769 NM_005290
GPR15
G protein-coupled receptor 15
chr13_-_45654296 0.765 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_+_49922592 0.765 DAZAP2
DAZ associated protein 2
chr10_+_5812616 0.762 C10orf18
chromosome 10 open reading frame 18
chr1_-_246869181 0.761 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chrX_-_54841397 0.757 NM_198510
ITIH5L
inter-alpha (globulin) inhibitor H5-like
chr4_-_186970366 0.753 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr3_-_49826360 0.750 NM_003335
UBA7
ubiquitin-like modifier activating enzyme 7
chr3_+_186563529 0.748 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr11_-_88436463 0.744 NM_000842
GRM5
glutamate receptor, metabotropic 5
chr11_-_64327197 0.741 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr17_-_44043278 0.736 HOXB7
homeobox B7
chr6_+_154449334 0.732 NM_001145287
OPRM1
opioid receptor, mu 1
chr2_-_215711313 0.722 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr14_+_69307914 0.722 SRSF5
serine/arginine-rich splicing factor 5

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.91 2.42e-10 GO:0002376 immune system process
2.17 1.89e-09 GO:0006955 immune response
2.65 6.96e-05 GO:0045321 leukocyte activation
4.59 7.04e-05 GO:0034340 response to type I interferon
2.14 1.66e-04 GO:0050776 regulation of immune response
2.78 2.88e-04 GO:0046649 lymphocyte activation
2.23 3.28e-04 GO:0045087 innate immune response
4.40 3.31e-04 GO:0060337 type I interferon-mediated signaling pathway
4.40 3.31e-04 GO:0071357 cellular response to type I interferon
2.71 8.28e-04 GO:0019221 cytokine-mediated signaling pathway
1.83 1.04e-03 GO:0002682 regulation of immune system process
2.52 2.78e-03 GO:0071345 cellular response to cytokine stimulus
3.10 4.08e-03 GO:0042110 T cell activation
1.94 4.15e-03 GO:0001775 cell activation
2.88 5.65e-03 GO:0050870 positive regulation of T cell activation
1.17 1.76e-02 GO:0050794 regulation of cellular process
2.55 2.25e-02 GO:0051251 positive regulation of lymphocyte activation
1.64 2.74e-02 GO:0006952 defense response
2.52 2.81e-02 GO:0050863 regulation of T cell activation
2.33 3.01e-02 GO:0051249 regulation of lymphocyte activation
1.16 3.39e-02 GO:0050789 regulation of biological process
3.63 4.88e-02 GO:0030217 T cell differentiation

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 6.65e-03 GO:0005515 protein binding